Prime Minister Antonis Samaras was due to leave Athens late on Monday to begin a three-day trip to the US, the highlight of which will be a meeting with President Barack Obama on Thursday.
Samaras is due in New York on Wednesday, when he will speak with Greek-American businessmen.
On Thursday, Samaras will meet Obama at the White House.
The following day, the Greek premier will return to New York, where he will meet Mayor Michael Bloomberg, United Nations Secretary-General Ban Ki-moon and the head of the American Jewish Committee, David Harris.
Samaras is also expected to visit Ground Zero and inspect the rebuilding work at St Nicholas Church, which was destroyed in the 9/11 attacks.
During his visit, Samaras is also due to meet the editorial boards of the New York Times and Washington Post.